免疫酚/犬尿氨酸抗体/IS010
市场价：
¥7400.00
美元价：
3700.00
产品分类：
生物安全柜
公司分类：
Biosafety_cabinet
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product information | Protocols | References | Technical support | Reviews |
Product overview
| Product name | Kynurenic acid antibody |
| Synonyms | Kinurenic acid antibody 4-Hydroxyquinoline-2-carboxylic acid antibodyKYNA antibody |
| Immunogen | Conjugated kynurenic acid |
| Isotype | IgG1 k chain |
| Clone | clone 4G12-A12 |
| Specificity | When tested in competitive ELISA, the anti-Kynurenic antibody 4G12-A12 did not show any significant cross reactivity with Quinaldic, Xanthurenic, Anthranilic, Picolinic or Quinolinic acid conjugates |
| Lot number | 140201 |
Storage
| Form | Liquid |
| Purity | Purified IgG |
| Concentration | 0,5 mg/ml |
| Storage | Store at +4°C for short term (1-2 months). Aliquot and store at -20°C for long term. Avoid repeated freeze / thaw cycles. |
| Material safety datasheet | Download MSDS |
Protocols
| Immunohistochemistry (IHC) | Dilute at 1:200-1:2000. Perform heat antigen retrieval (pH=6) before initiating IHC staining protocol on paraffin-embedded and frozen sections |
| Immunofluorescence (IF) | 1:100-1:1000 on paraffin-embedded and frozen sections. Before staining, perform heat antigen retrieval |
| Comments | Optimal working dilutions must be determined by the end-user |
| Restrictions | For research use only |
References
Antibody not yet cited. Submit an article and get a 10% discount.
Selected articles on Kynurenic acid:
- Justinova Z, Mascia P, Wu HQ, Secci ME, Redhi GH, Panlilio LV, Scherma M, Barnes C, Parashos A, Zara T, Fratta W, Solinas M, Pistis M, Bergman J, Kangas BD, Ferré S, Tanda G, Schwarcz R, Goldberg SR. Reducing cannabinoid abuse and preventing relapse by enhancing endogenous brain levels of kynurenic acid. Nat Neurosci. 2013 Nov;16(11):1652-61. doi: 10.1038/nn.3540. Epub 2013 Oct 13.
- StoneTW, Stoy N, Darlington LG. An expanding range of targets for kynureninemetabolites of tryptophan. Trends Pharmacol Sci. 2013 Feb;34(2):136-43.doi: 10.1016/j.tips.2012.09.006. Epub 2012 Nov 1.
- Schwarcz R, Bruno JP, Muchowski PJ, Wu HQ. Kynurenines in the mammalian brain: when physiology meets pathology. Nat Rev Neurosci. 2012 Jul;13(7):465-77. doi: 10.1038/nrn3257.
- Moroni F, Cozzi A, Sili M, Mannaioni G. Kynurenic acid: a metabolite with multiple actions and multiple targets in brain and periphery. J Neural Transm. 2012 Feb;119(2):133-9. doi: 10.1007/s00702-011-0763-x. Epub 2012 Jan 4.
- Linderholm KR, Skogh E, Olsson SK, Dahl ML, Holtze M, Engberg G, Samuelsson M, Erhardt S. Increased levels of kynurenine and kynurenic acid in the CSF of patients with schizophrenia. Schizophr Bull. 2012 May;38(3):426-32. doi: 10.1093/schbul/sbq086. Epub 2010 Aug 20.
- Stone TW, Forrest CM, Darlington LG. Kynurenine pathway inhibition as a therapeutic strategy for neuroprotection. FEBS J. 2012 Apr;279(8):1386-97. doi: 10.1111/j.1742-4658.2012.08487.x. Epub 2012 Mar 27.
Technical SupportSubmit a question
No technical question yet. Be the first to ask!TopReviewsSubmit your review
No reviews yet. Thanks for rating this product.Top品牌介绍
我们的重点：针对小分子的抗体ImmuSmol代表“针对小分子的免疫球蛋白[抗体]”。传统抗体只能识别蛋白质等大分子，而ImmuSmol设计并开发能够靶向低分子量实体（<900 Da）的抗体。因此，氨基酸，脂质，糖类，毒素，药物……实际上，任何小分子都可以以高亲和力和特异性来处理。与现有的基于抗体的技术完全兼容，小分子抗体为研究，诊断和治疗开辟了全新的可能性。三大核心应用研究抗体 -ImmuSmol销售经过验证的 一抗，用于细胞和组织中的小分子检测和可视化。定制服务 -ImmuSmol提供针对小分子的抗体，用于研究，诊断和治疗应用。诊断与治疗 -目前正在开发基于专有小分子抗体的三种个性化医学程序。
