Product information | Protocols | References | Technical support | Reviews |
Product overview
Product name | Quinolinic acid antibody |
Synonyms | Pyridine-2,3-dicarboxylic acid antibody 2,3-pyridinedicarboxylic acid antibody 3,4-Pyridinedicarboxylic acid antibody Pyridine-3,4-dicarboxylic acid antibody |
Immunogen | Conjugated quinolinic acid |
Isotype | IgG1 k chain |
Clone | clone 4E11-G3 |
Specificity | When tested in competitive ELISA, the anti-Quinolinic acid antibody did not show any significant cross reactivity with Picolinic and Quinaldic acid conjugates |
Lot number | 140201 |
Storage
Form | Liquid |
Purity | Purified IgG |
Concentration | 0,5 mg/ml |
Storage | Store at +4°C for short term (1-2 months). Aliquot and store at -20°C for long term. Avoid repeated freeze / thaw cycles. |
Material safety datasheet | Download MSDS |
Protocols
Immunohistochemistry (IHC) | Dilute at 1:100-1:1000. Perform heat antigen retrieval (pH=9) before initiating IHC staining protocol on paraffin-embedded and frozen sections |
Immunofluorescence (IF) | Dilute at 1:50-1:500 on paraffin-embedded and frozen sections. Perform heat antigen retrieval and incubate fluorescent dyes conjugated secondary antibody |
Comments | Optimal working dilutions must be determined by the end-user |
Restrictions | For research use only |
References
Antibody not yet cited. Submit an article and get a 10% discount!
Selected publications about Quinolinic acid:
- Lugo-Huitrón R, Ugalde Muñiz P, Pineda B, Pedraza-Chaverrí J, Ríos C, Pérez-de la Cruz V. Quinolinic acid: an endogenous neurotoxin with multiple targets. Oxid Med Cell Longev. 2013;2013:104024. doi: 10.1155/2013/104024. Epub 2013 Sep 5. Review.
- Wu W, Nicolazzo JA, Wen L, Chung R, Stankovic R, Bao SS, Lim CK, Brew BJ, Cullen KM, Guillemin GJ. Expressionof tryptophan 2,3-dioxygenase and production of kynurenine pathwaymetabolites in triple transgenic mice and human Alzheimer"s diseasebrain. PLoS One. 2013 Apr 22;8(4):e59749. doi: 10.1371/journal.pone.0059749. Print 2013
- SchwarczR, Bruno JP, Muchowski PJ, Wu HQ. Kynurenines in the mammalian brain:when physiology meets pathology. Nat Rev Neurosci. 2012Jul;13(7):465-77. doi: 10.1038/nrn3257.
- Guillemin GJ.Quinolinic acid, the inescapable neurotoxin.FEBS J. 2012 Apr;279(8):1356-65. doi: 10.1111/j.1742-4658.2012.08485.x. Epub 2012 Mar 27. Review
Technical SupportSubmit a question
No technical question yet. Be the first to ask!TopReviewsSubmit your review
No reviews yet. Thanks for rating this product.Top